Neurontin (Gabapentin) Side Effects

Neurontin side effects

When treating neuropathic pain

The main side effects that arose on the background of treatment in at least 1% of patients include:

  • Central and peripheral nervous system: confusion, ataxia, dizziness, amnesia, gait disturbance, drowsiness, impaired thinking, hypoesthesia, and tremor.
  • Digestive system: nausea, dry mouth, vomiting, flatulence, indigestion, abdominal pain, constipation, and diarrhea.
  • Respiratory system: pharyngitis, dyspnea.
  • Dermatological reactions: skin rashes.
  • Sense organs: amblyopia.
  • Other: infection, back pain, asthenia, headache, accidental trauma, weight gain, flu-like syndrome, and peripheral edema.

When treating partial seizures

The safety of Neurontin (Gabapentin) as an additional medication has been studied in more than 2000 patients; its tolerability was good. Gabapentin is most commonly used in combination with other anticonvulsants, so it is impossible to determine which drug (s) cause (s) side effects.

The main side effects that arose on the background of treatment in at least 1% of patients include:

  • Cardiovascular system: arterial hypertension or signs of vasodilation.
  • Central and peripheral nervous system: dizziness, hyperkinesia, hyperreflexia or hyporeflexia, anxiety, paresthesia, amnesia, hostility, ataxia, muscle twitching, mental confusion, depression, dysarthria, coordination disorder, insomnia, drowsiness, tremor, nystagmus, emotional lability, nervousness, and thought disorder.
  • Digestive system: anorexia, flatulence, constipation, gingivitis, abdominal pain, dental diseases, diarrhea, dry pharynx or dry mouth, dyspepsia, increased appetite, nausea, and vomiting.
  • Respiratory system: pneumonia, rhinitis, cough, and pharyngitis.
  • Sense organs: amblyopia, diplopia, and impaired vision.
  • Hematopoietic system: leukopenia and purpura (it was often described as sores that appeared in the case of physical trauma).
  • Musculoskeletal system: myalgia, back pain, fractures, and arthralgia.
  • Urinary system: urinary tract infection, impotence.
  • Dermatological reactions: skin itching, abrasions, acne, and skin rashes.
  • Other: facial swelling, asthenia, fatigue, fever, general malaise, peripheral edema, viral infection, headache, and weight gain.


The following side effects have been observed when performing additional therapy in children aged 3-12 years old with a frequency of about 2% and higher than with placebo.

  • Central and peripheral nervous system: hostility, drowsiness, emotional lability, hyperkinesia, and dizziness.
  • Respiratory system: bronchitis, and respiratory infection.
  • Digestive system: nausea, vomiting.
  • Other: headache, pharyngitis, diarrhea, rhinitis, anorexia, convulsions, cough, otitis media, fever, viral infection, fatigue, upper respiratory infections, and weight gain.

Symptoms of overdose: dizziness, drowsiness, double vision, speech disturbance, lethargy, and mild diarrhea. These manifestations have been observed with a single intake of the drug at a dose of 49g.


  1. As they say, I “chilled” my forehead. I experienced a “shooting” pain in the area between the eyebrows, the upper jaw. The neuralgia of the first branch of the trigeminal nerve was determined (it was bilateral, although one of the neurologists categorically asserted that bilateral trigeminal neuralgia never happens). I was prescribed Gabapentin and analgesics. It helped. But sometimes it appears again at the first serious hypothermia and I took Gabapentin and analgesics. It helped again. Droughts and cold are frequent phenomena, so I understand that I need to “wrap up in layers”.

  2. I was prescribed Gabapentin for treating a long-lasting pains in the shoulder joint. I’m taking gabapentin 2 capsules for 2 weeks at night, as it is at night that I experience a strong pain in my shoulder after a serious injury. First, I took 1 capsule (300 mg). But I did not help, switched to 2 – it helped, there are no special consequences. I like taking Gabapentin so that there are no consequences from it, and as you know, in the case of potent painkillers, the consequences are bad, as it is difficult to live a normal life during the day. So why I choose Gabapentin!

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